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Clinical trial efficacy data
Clinical trial efficacy data

Reduced risk of anemia in clinical trials1-3

  • Fewer red blood cell-related events from chemotherapy in patients taking COSELA in clinical trials, including1-4:
    • Grade 3/4 decreased hemoglobin (secondary and exploratory endpoints)
    • Red blood cell transfusions after week 5 (secondary and exploratory endpoints)
    • ESA administration (secondary and exploratory endpoints)
  • COSELA administration can cause injection-site reactions, including phlebitis and thrombophlebitis

1L=first-line; 2L=second-line; 3L=third-line; ESA=erythropoiesis-stimulating agent.

a
Adjusted relative risk=0.642 (95% CI: 0.294, 1.404).1
b
Adjusted relative risk=0.663 (95% CI: 0.336, 1.310).4
c
Adjusted relative risk=0.529 (95% CI: 0.145, 1.927).4
d
Study 2 was a proof-of-concept study with the primary objectives of assessing safety and tolerability; efficacy objectives were secondary or exploratory.2